Short and long-term photostability of 3D printed fluorescent phantoms for near-infrared diffuse optical imaging

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Item Type:	Conference or Workshop Item
Title:	Short and long-term photostability of 3D printed fluorescent phantoms for near-infrared diffuse optical imaging
Creators Name:	Schädel-Ebner, Sandra, Hirsch, Ole, Gladytz, T., Gutkelch, Dirk, Licha, Kai, Berger, Jörn and Grosenick, Dirk
Abstract:	We have successfully printed an anatomically shaped hand model with properties similar to in vivo investigations with a fluorescence hand imager using indocyanine green (ICG). By adding the fluorescent dye Lumogen IR 765, titanium dioxide powder and black ink to a 3D printing methacrylate photopolymer we realized phantoms with physiologically relevant absorption and reduced scattering coefficients as well as fluorescence properties similar to the widely applied contrast agent ICG. The phantoms show an excellent long-term photostability making them well suited for device performance monitoring and comparison. In contrast, fluorescence of phantoms printed with ICG continuously decreases over time.
Keywords:	3D Printing, 3D Image Processing, Diffuse Optical Imaging, Dyes, Fluorescence, Diseases and Disorders, Fluorescence Imaging, Imaging systems, Materials Properties, Printing
Source:	Proceedings of SPIE
Title of Book:	Diffuse Optical Spectroscopy and Imaging IX
ISSN:	0277-786X
ISBN:	978-151066465-4
Publisher:	SPIE
Page Range:	126281A
Date:	9 August 2023
Official Publication:	https://doi.org/10.1117/12.2670658

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