A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma

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Item Type:	Editorial
Title:	A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma
Creators Name:	Deubzer, H.E., Astrahantseff, K. and Lodrini, M.
Abstract:	Single biopsies fail to reflect intratumor heterogeneity and tumor evolution. In this issue of Cancer Discovery, Bosse and colleagues show an important role for circulating cell-free tumor DNA sequencing to detect the genomic evolution of neuroblastoma under ALK inhibitor therapy and identify novel (sub)clonal pathogenic variants involved in disease progression under conventional therapy. See related article by Bosse et al., p. 2800 (5).
Keywords:	Acetaminophen, Aspirin, Cell-Free Nucleic Acids, Circulating Tumor DNA, Genomics, Neuroblastoma
Source:	Cancer Discovery
ISSN:	2159-8274
Publisher:	American Association for Cancer Research
Volume:	12
Number:	12
Page Range:	2727-2729
Date:	2 December 2022
Official Publication:	https://doi.org/10.1158/2159-8290.cd-22-1023
PubMed:	View item in PubMed

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