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| Item Type: | Editorial |
|---|---|
| Title: | Blood flow meets mitophagy |
| Creators Name: | Akmeriç, E.B. and Gerhardt, H. |
| Abstract: | Since its discovery as a mechanosensitive transcription factor in endothelial networks, Klf2's varying expression levels under different blood flow patterns remained a mystery. In this study, Coon et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202109144) discover a connection between sustained laminar shear stress and mitochondrial flux that contributes to Klf2's transcriptional dynamics. |
| Keywords: | Cell Metabolism, Cell Signaling, Disease, Metabolism, Animals, Mice |
| Source: | Journal of Cell Biology |
| ISSN: | 0021-9525 |
| Publisher: | Rockefeller University Press |
| Volume: | 221 |
| Number: | 7 |
| Page Range: | e202206033 |
| Date: | 4 July 2022 |
| Official Publication: | https://doi.org/10.1083/jcb.202206033 |
| PubMed: | View item in PubMed |
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