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| Item Type: | Editorial |
|---|---|
| Title: | The blood-brain barrier-a metabolic ecosystem |
| Creators Name: | Castro, M. and Potente, M. |
| Abstract: | A functional blood-brain barrier relies on a tightly controlled interplay between endothelial cells, pericytes, and astrocytes, which together form the neurovascular unit. Recent work by Lee et al (2022) discovers endothelial cell-derived lactate as a crucial metabolic fuel for brain pericytes, revealing a new way of CNS vascular communication that links nutrient metabolism to blood-brain barrier function. |
| Keywords: | Astrocytes, Blood-Brain Barrier, Brain, Ecosystem, Endothelial Cells, Pericytes / Metabolism |
| Source: | EMBO Journal |
| ISSN: | 0261-4189 |
| Publisher: | EMBO Press / Wiley |
| Volume: | 41 |
| Number: | 9 |
| Page Range: | e111189 |
| Date: | 2 May 2022 |
| Additional Information: | Copyright © 2022 The Authors |
| Official Publication: | https://doi.org/10.15252/embj.2022111189 |
| External Fulltext: | View full text on PubMed Central |
| PubMed: | View item in PubMed |
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