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Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome

Item Type:Article
Title:Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome
Creators Name:Borowski, S., Freitag, N., Urban, I., Michel, G., Barrientos, G. and Blois, S.M.
Abstract:Galectin-1 (gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, is differentially expressed at the feto-maternal interface and appears to be functionally polyvalent, with a wide range of biological activities. However, the contributions of maternal and/or feto-placental gal-1 to the signaling networks promoting a healthy pregnancy are still being elucidated. This chapter discusses the methods commonly employed to study the maternal or feto-placental contribution of gal-1 during pregnancy in mice. The methods described here can be used to decipher the specific role of each source, e.g., maternal and/or feto-placental derived gal-1 in the orchestration of pregnancy-associated processes.
Keywords:Galectin-1, Maternal and Placental Galectin-1 Models, Pregnancy Outcome, Lectin Staining, In Vitro Fertilization, Animals, Mice
Source:Methods in Molecular Biology
Series Name:Methods in Molecular Biology
Title of Book:Galectins
ISSN:1064-3745
ISBN:978-1-0716-2054-0
Publisher:Springer / Humana Press
Volume:2442
Page Range:603-619
Date:2022
Official Publication:https://doi.org/10.1007/978-1-0716-2055-7_32
PubMed:View item in PubMed

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