Item Type: | Editorial |
---|---|
Title: | A resource of targeted mutant mouse lines for 5,061 genes |
Creators Name: | Birling, M.C., Yoshiki, A., Adams, D.J., Ayabe, S., Beaudet, A.L., Bottomley, J., Bradley, A., Brown, S.D.M., Bürger, A., Bushell, W., Chiani, F., Chin, H.J.G., Christou, S., Codner, G.F., DeMayo, F.J., Dickinson, M.E., Doe, B., Donahue, L.R., Fray, M.D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L.O., Heaney, J.D., Hérault, Y., de Angelis, M.H., Jiang, S.T., Justice, M.J., Kasparek, P., King, R.E., Kühn, R., Lee, H., Lee, Y.J., Liu, Z., Lloyd, K.C.K., Lorenzo, I., Mallon, A.M., McKerlie, C., Meehan, T.F., Fuentes, V.M., Newman, S., Nutter, L.M.J., Oh, G.T., Pavlovic, G., Ramirez-Solis, R., Rosen, B., Ryder, E.J., Santos, L.A., Schick, J., Seavitt, J.R., Sedlacek, R., Seisenberger, C., Seong, J.K., Skarnes, W.C., Sorg, T., Steel, K.P., Tamura, M., Tocchini-Valentini, G.P., Wang, C.K.L., Wardle-Jones, H., Wattenhofer-Donzé, M., Wells, S., Wiles, M.V., Willis, B.J., Wood, J.A., Wurst, W., Xu, Y., Teboul, L. and Murray, S.A. |
Abstract: | The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles. |
Keywords: | Gene Deletion, Genetic Association Studies, Genome, Genotype, Information Dissemination, International Cooperation, Internet, Knockout Mice, Mouse Embryonic Stem Cells, Mutagenesis, Phenotype, Animals, Mice |
Source: | Nature Genetics |
ISSN: | 1061-4036 |
Publisher: | Nature Publishing Group |
Volume: | 53 |
Number: | 4 |
Page Range: | 416-419 |
Date: | April 2021 |
Official Publication: | https://doi.org/10.1038/s41588-021-00825-y |
PubMed: | View item in PubMed |
Repository Staff Only: item control page