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Differenzialdiagnostik autoimmun-entzündlicher Rückenmarkserkrankungen [Differential diagnostics of autoimmune inflammatory spinal cord diseases]

Item Type:Article
Title:Differenzialdiagnostik autoimmun-entzündlicher Rückenmarkserkrankungen [Differential diagnostics of autoimmune inflammatory spinal cord diseases]
Creators Name:Oertel, F.C., Scheel, M., Chien, C., Bischof, A., Finke, C. and Paul, F.
Abstract:Myelitis is an acute or subacute inflammatory syndrome of the spinal cord. Myelopathy, often used as a synonym and presenting with similar symptoms in clinical practice, can be caused by numerous, not primarily inflammatory etiologies and might also show a progressive disease course. Within the last decade the spectrum of autoimmune myelitis was significantly broadened as was the spectrum of diagnostic methods. Apart from the characteristic example of multiple sclerosis with short-length myelitis and neuromyelitis optica spectrum disorders with longitudinally extensive transverse myelitis, multiple rare but important differential diagnoses should also be considered. Magnetic resonance imaging and laboratory analyses of serum antibodies and cerebrospinal fluid are the most important diagnostic methods and are fundamental for rapid treatment decisions, subsequently with better prognosis. This article reviews representative diseases within the spectrum of autoimmune spinal cord diseases and their differential diagnoses.
Keywords:Autoimmune Systemic Diseases, Symptoms, Myelitis, Multiple Sclerosis, Neuromyelitis Optica
Source:Nervenarzt
ISSN:0028-2804
Publisher:Springer
Volume:92
Number:4
Page Range:293-306
Date:April 2021
Additional Information:Copyright © Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2021
Official Publication:https://doi.org/10.1007/s00115-021-01092-2
External Fulltext:View full text on PubMed Central
PubMed:View item in PubMed

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