![[feed]](/style/images/feed-icon-14x14.png){kind=icon}
Tools
Tools
Preview |
PDF (Original Article)
- Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
286kB |
| Item Type: | Article |
|---|---|
| Title: | Use of statins in lower extremity artery disease: a review |
| Creators Name: | Gargiulo, G., Giugliano, G., Brevetti, L., Sannino, A., Schiattarella, G.G., Serino, F., Carbone, A., Scudiero, F., Ferrone, M., Corrado, R., Izzo, R., Chiariotti, L., Perrino, C., Amato, B., Trimarco, B. and Esposito, G. |
| Abstract: | BACKGROUND: Lower extremity artery disease (LE-PAD) is one of the most common manifestations of atherosclerosis, particularly in elderly patients, and it is related to a high cardiovascular risk. DESCRIPTION: It is well established that statin therapy is characterized by crucial benefits on cardiovascular system by limiting atherosclerotic progression and reducing cardiovascular events and mortality. A growing body of evidence support efficacy of statins in LE-PAD due to the ability of both reducing cardiovascular risk and improving walking distance and, hence, quality of life. Consequently, statin therapy should be considered in all LE-PAD patients and new LDL-cholesterol targets should be reached. CONCLUSIONS: Our opinion is that statin therapy remains still underutilized or with inadequate dosage, so therapy of LE-PAD patients should be improved to obtain all the demonstrated benefits of statins. |
| Keywords: | Simvastatin, Pravastatin, Statin Therapy, Pentoxifylline, Cilostazol |
| Source: | BMC Surgery |
| ISSN: | 1471-2482 |
| Publisher: | BioMed Central |
| Volume: | 12 |
| Number: | Suppl 1 |
| Page Range: | S15 |
| Date: | 15 November 2012 |
| Official Publication: | https://doi.org/10.1186/1471-2482-12-S1-S15 |
| PubMed: | View item in PubMed |
Repository Staff Only: item control page
