Muscle

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Item Type:	Book Section
Title:	Muscle
Creators Name:	Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
Abstract:	In all three types of muscle cells - skeletal, cardiac, and smooth – Ca(2+) plays a major role in excitation-contraction (EC) coupling, i.e., the sequence of events that links electrical stimulation to contraction (or, in nonexcitable smooth muscle, the events that link agonist stimulation to contraction). In skeletal and cardiac muscle, an action potential arriving from a neuron is propagated along the membrane of the muscle cell, and penetrates deep into the interior of the cell via invaginations of the cell membrane, called T-tubules. This action potential causes the release of Ca(2+) from the sarcoplasmic reticulum, which then allows the crossbridge cycle to develop force (Huxley, 1957; Bers, 2001).
Keywords:	Smooth Muscle, Sarcoplasmic Reticulum, Airway Smooth Muscle, Myosin Light Chain Kinase, Release Unit
Series Name:	Interdisciplinary Applied Mathematics
Title of Book:	Models of Calcium Signalling
ISSN:	0939-6047
ISBN:	978-3-319-29645-6
Publisher:	Springer
Volume:	43
Page Range:	295-336
Date:	2016
Official Publication:	https://doi.org/10.1007/978-3-319-29647-0_7
Related to:	URL URL Type https://edoc.mdc-berlin.de/15812/ Book

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