Perivascular fibrosis and the microvasculature of the heart. still hidden secrets of pathophysiology?

Tools

Item Type:	Review
Title:	Perivascular fibrosis and the microvasculature of the heart. still hidden secrets of pathophysiology?
Creators Name:	Ytrehus, K., Hulot, J.S., Perrino, Cinzia, Schiattarella, G.G. and Madonna, R.
Abstract:	Perivascular fibrosis, the deposition of connective tissue around the vessels, has been demonstrated crucially involved in the development of cardiac dysfunction. Although cardiac fibrosis has been shown to be reversible under certain experimental conditions, effective anti-fibrotic therapies remain largely elusive. Therefore, perivascular fibrosis currently represents a major therapeutic target for cardiovascular diseases. The main topic of this review will be to address the mechanisms underlying perivascular fibrosis of the vasculature within the myocardium, with a special focus on perivascular fibrosis of small vessels, microvascular dysfunction and disease.
Source:	Vascular Pharmacology
ISSN:	1537-1891
Publisher:	Elsevier
Volume:	107
Page Range:	78-83
Date:	August 2018
Official Publication:	https://doi.org/10.1016/j.vph.2018.04.007
PubMed:	View item in PubMed

Repository Staff Only: item control page