Item Type: | Article |
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Title: | Hold me, but not too tight - endothelial cell-cell junctions in angiogenesis |
Creators Name: | Szymborska, A. and Gerhardt, H. |
Abstract: | Endothelial cell-cell junctions must perform seemingly incompatible tasks during vascular development-providing stable connections that prevent leakage, while allowing dynamic cellular rearrangements during sprouting, anastomosis, lumen formation, and functional remodeling of the vascular network. This review aims to highlight recent insights into the molecular mechanisms governing endothelial cell-cell adhesion in the context of vascular development. |
Keywords: | Endothelial Cells, Intercellular Junctions, Physiologic Neovascularization, Vertebrates, Animals |
Source: | Cold Spring Harbor Perspectives in Biology |
ISSN: | 1943-0264 |
Publisher: | Cold Spring Harbor Laboratory Press |
Volume: | 10 |
Number: | 8 |
Page Range: | a029223 |
Date: | August 2018 |
Official Publication: | https://doi.org/10.1101/cshperspect.a029223 |
PubMed: | View item in PubMed |
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