Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Hold me, but not too tight - endothelial cell-cell junctions in angiogenesis

Item Type:Article
Title:Hold me, but not too tight - endothelial cell-cell junctions in angiogenesis
Creators Name:Szymborska, A. and Gerhardt, H.
Abstract:Endothelial cell-cell junctions must perform seemingly incompatible tasks during vascular development-providing stable connections that prevent leakage, while allowing dynamic cellular rearrangements during sprouting, anastomosis, lumen formation, and functional remodeling of the vascular network. This review aims to highlight recent insights into the molecular mechanisms governing endothelial cell-cell adhesion in the context of vascular development.
Keywords:Endothelial Cells, Intercellular Junctions, Physiologic Neovascularization, Vertebrates, Animals
Source:Cold Spring Harbor Perspectives in Biology
ISSN:1943-0264
Publisher:Cold Spring Harbor Laboratory Press
Volume:10
Number:8
Page Range:a029223
Date:August 2018
Official Publication:https://doi.org/10.1101/cshperspect.a029223
PubMed:View item in PubMed

Repository Staff Only: item control page

Open Access
MDC Library