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| Item Type: | Editorial |
|---|---|
| Title: | Examining topological domain influence on enhancer function |
| Creators Name: | Beagrie, R.A. and Pombo, A. |
| Abstract: | Enhancers regulate the expression of target genes across large genomic distances, but it is unclear how recently discovered topological domains affect this regulation. Reporting in this issue of Developmental Cell, Symmons et al. (2016) show that the endogenous Shh topological domain promotes functional interactions between Shh and its remote enhancer. |
| Keywords: | Genetic Enhancer Elements, Developmental Gene Expression Regulation |
| Source: | Developmental Cell |
| ISSN: | 1534-5807 |
| Publisher: | Cell Press |
| Volume: | 39 |
| Number: | 5 |
| Page Range: | 523-524 |
| Date: | 5 December 2016 |
| Official Publication: | https://doi.org/10.1016/j.devcel.2016.11.011 |
| PubMed: | View item in PubMed |
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