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| Item Type: | Review |
|---|---|
| Title: | Neuregulin/ErbB signaling in developmental myelin formation and nerve repair |
| Creators Name: | Birchmeier, C. and Bennett, D.L.H. |
| Abstract: | Myelin is essential for rapid and accurate conduction of electrical impulses by axons in the central and peripheral nervous system (PNS). Myelin is formed in the early postnatal period, and developmental myelination in the PNS depends on axonal signals provided by Nrg1/ErbB receptors. In addition, Nrg1 is required for effective nerve repair and remyelination in adulthood. We discuss here similarities and differences in Nrg1/ErbB functions in developmental myelination and remyelination after nerve injury. |
| Keywords: | Myelination, Remyelination, Peripheral Nervous System, Nrg1, Animals |
| Source: | Current Topics in Developmental Biology |
| Series Name: | Current Topics in Developmental Biology |
| Title of Book: | Essays on Developmental Biology, Part A |
| ISSN: | 0070-2153 |
| ISBN: | 978-0-12-802956-5 |
| Publisher: | Elsevier |
| Volume: | 116 |
| Page Range: | 45-64 |
| Number of Pages: | 744 |
| Date: | 2016 |
| Official Publication: | https://doi.org/10.1016/bs.ctdb.2015.11.009 |
| PubMed: | View item in PubMed |
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