The ERGonomics of hematopoietic stem cell self-renewal

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Item Type:	Article
Title:	The ERGonomics of hematopoietic stem cell self-renewal
Creators Name:	Lacadie, S.A. and Zon, L.I.
Abstract:	Stem cells make more of themselves by self-renewing cell divisions. In the February 1, 2011, issue of Genes and Development, Taoudi and colleagues (pp. 251-262) show an essential role for the ETS transcription factor ERG in the self-renewal of embryonic hematopoietic stem cells. A model is presented in which the redundant functions of GATA2 and RUNX1 in self-renewal are under direct control of ERG.
Keywords:	ERG, ETS Family Transcription Factors, Gata2, Hematopoietic Development, Hematopoietic Stem Cells, Runx1, Self-Renewal
Source:	Genes & Development
ISSN:	0890-9369
Publisher:	Cold Spring Harbor Laboratory Press
Volume:	25
Number:	4
Page Range:	289-293
Date:	15 February 2011
Official Publication:	https://doi.org/10.1101/gad.2031511
PubMed:	View item in PubMed

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