Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation

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Item Type:	Article
Title:	Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation
Creators Name:	Oberender, C., Kleeberg, L., Nienhues, N., Gresse, M., Doerken, B., Riess, H. and le Coutre, P.
Abstract:	Chronic myeloid leukemia developing after transplantation of solid organs and concomitant immunosuppression is a rare but still significant clinical phenomenon. We here describe an additional case of a 62-year-old male patient developing CML after orthotopic heart transplantation and medication with cyclosporine A, mofetil-mycophenolate, and steroids. Initial antileukemic therapy was imatinib at a standard dose and within 15 months of therapy a complete cytogenetic response was noted. In this report we discuss the clinical implications of these rare but biologically important cases.
Source:	Case Reports in Hematology
ISSN:	2090-6579
Publisher:	Hindawi
Volume:	2014
Page Range:	890438
Date:	16 November 2014
Official Publication:	https://doi.org/10.1155/2014/890438
PubMed:	View item in PubMed

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