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| Item Type: | Editorial |
|---|---|
| Title: | Mixed messages: re-initiation factors regulate translation of animal mRNAs |
| Creators Name: | Obermayer, B. and Rajewsky, N. |
| Abstract: | When ribosomes encounter upstream open reading frames (uORFs) during scanning of the 5' untranslated region (5' UTR), translation of the downstream ORF requires re-initiation. In a recent paper in Nature, Schleich et al. describe metazoan factors which specifically promote re-initiation. |
| Keywords: | Drosophila Proteins, Eukaryotic Initiation Factors, Gene Expression Regulation, Protein Biosynthesis, Animals, Drosophila |
| Source: | Cell Research |
| ISSN: | 1001-0602 |
| Publisher: | Nature Publishing Group |
| Volume: | 24 |
| Number: | 12 |
| Page Range: | 1383-1384 |
| Date: | December 2014 |
| Official Publication: | https://doi.org/10.1038/cr.2014.114 |
| PubMed: | View item in PubMed |
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