Mixed messages: re-initiation factors regulate translation of animal mRNAs

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Item Type:	Editorial
Title:	Mixed messages: re-initiation factors regulate translation of animal mRNAs
Creators Name:	Obermayer, B. and Rajewsky, N.
Abstract:	When ribosomes encounter upstream open reading frames (uORFs) during scanning of the 5' untranslated region (5' UTR), translation of the downstream ORF requires re-initiation. In a recent paper in Nature, Schleich et al. describe metazoan factors which specifically promote re-initiation.
Keywords:	Drosophila Proteins, Eukaryotic Initiation Factors, Gene Expression Regulation, Protein Biosynthesis, Animals, Drosophila
Source:	Cell Research
ISSN:	1001-0602
Publisher:	Nature Publishing Group
Volume:	24
Number:	12
Page Range:	1383-1384
Date:	December 2014
Official Publication:	https://doi.org/10.1038/cr.2014.114
PubMed:	View item in PubMed

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