A mitochondrial strategy for safeguarding the reprogrammed genome

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Item Type:	Comment
Title:	A mitochondrial strategy for safeguarding the reprogrammed genome
Creators Name:	Prigione, A. and Adjaye, J.
Abstract:	Genomic aberrations induced by somatic cell reprogramming are a major drawback for future applications of this technology in regenerative medicine. A new study by Ji et al. published in Stem Cell Reports suggests a counteracting strategy based on balancing the mitochondrial/oxidative stress pathway through antioxidant supplementation.
Keywords:	Antioxidants, Mitochondria, Reprogramming, iPSCs, Genomic Aberrations
Source:	Cell Regeneration
ISSN:	2045-9769
Publisher:	BioMed Central
Volume:	3
Number:	1
Page Range:	5
Date:	29 March 2014
Official Publication:	https://doi.org/10.1186/2045-9769-3-5
PubMed:	View item in PubMed

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