Item Type: | Editorial |
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Title: | It's the peptide-MHC affinity, stupid |
Creators Name: | Kammertoens, T. and Blankenstein, T. |
Abstract: | Adoptively transferred T cells can reject large established tumors, but recurrence due to escape variants frequently occurs. In this issue of Cancer Cell, Engels et al. demonstrate that the affinity of the target peptide to the MHC molecule determines whether large tumors will relapse following adoptive T cell therapy. |
Source: | Cancer Cell |
ISSN: | 1535-6108 |
Publisher: | Cell Press / Elsevier |
Volume: | 23 |
Number: | 4 |
Page Range: | 429-431 |
Date: | 15 April 2013 |
Additional Information: | Comment on: Cancer Cell 23(4):516-26 |
Official Publication: | https://doi.org/10.1016/j.ccr.2013.04.004 |
PubMed: | View item in PubMed |
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