Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs

Tools

Item Type:	Article
Title:	Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs
Creators Name:	Leutz, A., Pless, O., Lappe, M., Dittmar, G. and Kowenz-Leutz, E.
Abstract:	C/EBPs regulate tissue and cell type specific gene expression, proliferation and differentiation control. C/EBPs assist in energy metabolism, female reproduction, innate immunity, inflammation, senescence and the development of neoplasms. How can C/EBPs fulfill so many functions? Here we discuss that C/EBPs are extensively modified by methylation of arginine and lysine side chains and that regulated methylation profoundly affects the activity of C/EBPs.
Keywords:	Transcription, Chromatin Remodeling, Differentiation, Histone Code, Post-Translational Modification, Signaling, Methylation, Animals
Source:	Transcription
ISSN:	2154-1264
Publisher:	Landes Bioscience
Volume:	2
Number:	1
Page Range:	3-8
Date:	January 2011
Official Publication:	https://doi.org/10.4161/trns.2.1.13510
PubMed:	View item in PubMed

Repository Staff Only: item control page