Item Type: | Article |
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Title: | Plasma folate, related genetic variants, and colorectal cancer risk in EPIC |
Creators Name: | Eussen, S.J., Vollset, S.E., Igland, J., Meyer, K., Fredriksen, A., Ueland, P.M., Jenab, M., Slimani, N., Boffetta, P., Overvad, K., Tjonneland, A., Olsen, A., Clavel-Chapelon, F., Boutron-Ruault, M.C., Morois, S., Weikert, C., Pischon, T., Linseisen, J., Kaaks, R., Trichopoulou, A., Zilis, D., Katsoulis, M., Palli, D., Berrino, F., Vineis, P., Tumino, R., Panico, S., Peeters, P.H., Bueno-de-Mesquita, H.B., van Duijnhoven, F.J., Gram, I.T., Skeie, G., Lund, E., Gonzalez, C.A., Martinez, C., Dorronsoro, M., Ardanaz, E., Navarro, C., Rodriguez, L., Van Guelpen, B., Palmqvist, R., Manjer, J., Ericson, U., Bingham, S., Khaw, K.T., Norat, T. and Riboli, E. |
Abstract: | A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort. |
Keywords: | Case-Control Studies, Colorectal Neoplasms, Folic Acid, Genetic Predisposition to Disease, Methylenetetrahydrofolate Reductase (NADPH2), Single Nucleotide Polymorphism, Prognosis, Prospective Studies, Risk Factors, Survival Rate |
Source: | Cancer Epidemiology Biomarkers & Prevention |
ISSN: | 1055-9965 |
Publisher: | American Association for Cancer Research |
Volume: | 19 |
Number: | 5 |
Page Range: | 1328-1340 |
Date: | May 2010 |
Official Publication: | https://doi.org/10.1158/1055-9965.EPI-09-0841 |
PubMed: | View item in PubMed |
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