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Plasma folate, related genetic variants, and colorectal cancer risk in EPIC

Item Type:Article
Title:Plasma folate, related genetic variants, and colorectal cancer risk in EPIC
Creators Name:Eussen, S.J., Vollset, S.E., Igland, J., Meyer, K., Fredriksen, A., Ueland, P.M., Jenab, M., Slimani, N., Boffetta, P., Overvad, K., Tjonneland, A., Olsen, A., Clavel-Chapelon, F., Boutron-Ruault, M.C., Morois, S., Weikert, C., Pischon, T., Linseisen, J., Kaaks, R., Trichopoulou, A., Zilis, D., Katsoulis, M., Palli, D., Berrino, F., Vineis, P., Tumino, R., Panico, S., Peeters, P.H., Bueno-de-Mesquita, H.B., van Duijnhoven, F.J., Gram, I.T., Skeie, G., Lund, E., Gonzalez, C.A., Martinez, C., Dorronsoro, M., Ardanaz, E., Navarro, C., Rodriguez, L., Van Guelpen, B., Palmqvist, R., Manjer, J., Ericson, U., Bingham, S., Khaw, K.T., Norat, T. and Riboli, E.
Abstract:A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort.
Keywords:Case-Control Studies, Colorectal Neoplasms, Folic Acid, Genetic Predisposition to Disease, Methylenetetrahydrofolate Reductase (NADPH2), Single Nucleotide Polymorphism, Prognosis, Prospective Studies, Risk Factors, Survival Rate
Source:Cancer Epidemiology Biomarkers & Prevention
ISSN:1055-9965
Publisher:American Association for Cancer Research
Volume:19
Number:5
Page Range:1328-1340
Date:May 2010
Official Publication:https://doi.org/10.1158/1055-9965.EPI-09-0841
PubMed:View item in PubMed

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