Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

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Item Type:	Article
Title:	Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
Creators Name:	Jarius, S., Franciotta, D., Paul, F., Ruprecht, K., Bergamaschi, R., Rommer, P.S., Reuss, R., Probst, C., Kristoferitsch, W., Wandinger, K.P. and Wildemann, B.
Abstract:	In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO.
Keywords:	Aquaporin 4, Autoantibodies, Neuromyelitis Optica, Nonparametric Statistics, Sensitivity and Specificity
Source:	Journal of Neuroinflammation
ISSN:	1742-2094
Publisher:	BioMed Central
Volume:	7
Page Range:	52
Date:	8 September 2010
Official Publication:	https://doi.org/10.1186/1742-2094-7-52
PubMed:	View item in PubMed

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