Quasi-steady approximation for ion channel currents

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Item Type:	Article
Title:	Quasi-steady approximation for ion channel currents
Creators Name:	Bentele, K. and Falcke, M.
Abstract:	Currents through ion channels are determined (among other parameters) by the concentration difference across the membrane containing the channel and the diffusive transport of the conducted ion toward the channel and away from it. Calculation of the current requires solving the diffusion equation around the channel. Here, we provide a quasi-steady approximation for the current and the local concentrations at the channel together with formulas linking the current and local concentrations at the channel to bulk concentrations and diffusion properties of the compartments.
Keywords:	Biological Models, Cell Membrane, Chemical Models, Computer Simulation, Electric Impedance, Ion Channel Gating, Ion Channels, Membrane Potentials
Source:	Biophysical Journal
ISSN:	0006-3495
Publisher:	Biophysical Society
Volume:	93
Number:	8
Page Range:	2597-2608
Date:	15 October 2007
Official Publication:	https://doi.org/10.1529/biophysj.107.104299
PubMed:	View item in PubMed

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