Regression of high-grade gastric B-cell lymphoma after eradication of Helicobacter pylori

Item Type:	Article
Title:	Regression of high-grade gastric B-cell lymphoma after eradication of Helicobacter pylori
Creators Name:	Gretschel, S. and Huenerbein, M. and Foss, H.D. and Krause, M. and Schlag, P.M.
Abstract:	Regression of high-grade gastric B-cell lymphoma after eradication of Helicobacter pylori with antibiotic therapy has recently been shown in a very small number of patients. We describe here a patient with a 5-cm polypoid gastric lymphoma, who received a 7-day course of triple therapy when the histopathology was unknown. A second endoscopic examination 4 weeks later showed partial tumor regression without biopsy evidence of malignancy. Endoscopic mucosectomy was performed 8 weeks after the initial diagnosis. Again, in the histological analysis of the specimen, no evidence of B-cell lymphoma could be found. To confirm that the original biopsies were from the same patient, DNA analyses were carried out which gave identical results. This case suggests that a subgroup of primary gastric B-cell lymphomas responds to eradication of H. pylori with antibiotic therapy.
Keywords:	Anti-Bacterial Agents, B-Cell Lymphoma, Helicobacter Infections, Helicobacter Pylori, Non-Hodgkin Lymphoma, Regression Analysis, Remission Induction, Stomach Neoplasms
Source:	Endoscopy
ISSN:	0013-726X
Publisher:	Thieme
Volume:	33
Number:	9
Page Range:	805-807
Date:	September 2001
Official Publication:	https://doi.org/10.1055/s-2001-16527
PubMed:	View item in PubMed

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