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| Item Type: | Editorial |
|---|---|
| Title: | Shared sugars - parasite glycan homology in HIV-1 vaccine design |
| Creators: |
Deimel, L.P.  ORCID: https://orcid.org/0000-0003-3803-871X and Sattentau, Q.J. ORCID: https://orcid.org/0000-0001-7170-1937
|
| Abstract: | Immune tolerance to self-glycans is a host mechanism to avoid autoimmunity, which is exploited by HIV-1 coating its envelope glycoproteins with glycans to evade neutralising antibodies (nAbs). Huettner et al. describe cross-reactivity between Schistosoma mansoni glycans and HIV-1 envelope glycoprotein glycans, suggesting a strategy for induction of HIV-1 nAbs by vaccination. |
| Keywords: | HIV-1, Antibody, Glycan, Parasite, Helminth, Animals |
| Source: | Trends in Parasitology |
| ISSN: | 1471-4922 |
| Publisher: | Elsevier |
| Volume: | 38 |
| Number: | 7 |
| Page Range: | 498-500 |
| Date: | July 2022 |
| Official Publication: | https://doi.org/10.1016/j.pt.2022.04.001 |
| PubMed: | View item in PubMed |
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