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ATACing single cells with phages

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Item Type:Editorial
Title:ATACing single cells with phages
Creators Name:Maschmeyer, P. and Haas, S.
Abstract:Fiskin et al. (2021) developed a "multi-omics" approach that integrates phage-displayed single-domain antibodies ("nanobodies") with the assay for transposase-accessible chromatin (PHAGE-ATAC) to simultaneously determine protein expression, chromatin accessibility, and mitochondrial DNA mutations (for clonal tracing) in single cells.
Keywords:Bacteriophages, Chromatin, High-Throughput Nucleotide Sequencing, DNA Sequence Analysis, Transposases
Source:Molecular Cell
ISSN:1097-2765
Publisher:Cell Press
Volume:82
Number:2
Page Range:234-236
Date:20 January 2022
Additional Information:Copyright © 2021. This manuscript version is made available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.
Official Publication:https://doi.org/10.1016/j.molcel.2021.12.028
PubMed:View item in PubMed

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