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| Item Type: | Editorial |
|---|---|
| Title: | Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9 |
| Creators Name: | Kühn, R. and Chu, V.T. |
| Abstract: | The CRISPR-Cas9 system is frequently used to create small deletions in the genomes of mammalian cells, but the isolation of precisely targeted mutants is still challenging. A new, two-step 'pop in & out' targeting approach facilitates this task. |
| Keywords: | CRISPR-Cas Systems, Cell Line, Gene Targeting, Genome, Mutation, RNA Editing, Animals, Mammals |
| Source: | Genome Biology |
| ISSN: | 1465-6906 |
| Publisher: | BioMed Central |
| Volume: | 16 |
| Number: | 1 |
| Page Range: | 244 |
| Date: | 10 November 2015 |
| Official Publication: | https://doi.org/10.1186/s13059-015-0810-2 |
| PubMed: | View item in PubMed |
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