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Molecular eco-systems biology: towards an understanding of community function

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Item Type:Review
Title:Molecular eco-systems biology: towards an understanding of community function
Creators Name:Raes, J. and Bork, P.
Abstract:Systems-biology approaches, which are driven by genome sequencing and high-throughput functional genomics data, are revolutionizing single-cell-organism biology. With the advent of various high-throughput techniques that aim to characterize complete microbial ecosystems (metagenomics, meta-transcriptomics and meta-metabolomics), we propose that the time is ripe to consider molecular systems biology at the ecosystem level (eco-systems biology). Here, we discuss the necessary data types that are required to unite molecular microbiology and ecology to develop an understanding of community function and discuss the potential shortcomings of these approaches.
Keywords:Bacteria, Ecosystem, Genomics, Metabolomics, Microbiology, Theoretical Models, Proteomics, Systems Biology
Source:Nature Reviews Microbiology
ISSN:1740-1526
Publisher:Nature Publishing Group (U.K.)
Volume:6
Number:9
Page Range:693-699
Date:September 2008
Official Publication:https://doi.org/10.1038/nrmicro1935
PubMed:View item in PubMed

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