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The connection between actin ATPase and polymerization

Item Type:Article
Title:The connection between actin ATPase and polymerization
Creators Name:Schueler, H., Karlsson, R., Schutt, C.E. and Lindberg, U.
Abstract:Remodeling of the actin filament system in cells results from strictly regulated polymerization and depolymerization of actin, where hydrolysis of actinhyphenbound ATP is crucial. Actin–actin interactions are influenced by the state of the bound nucleotide, and many microfilament regulators influence the actin ATPase by binding preferentially either to ATP/ADP·Pihyphen or ADPhyphenbound actin. This chapter summarizes observations made concerning the actin ATPase and its role in the biological activity of actin and actin filaments.
Source:Advances in Molecular and Cell Biology
ISSN:1569-2558
Publisher:Elsevier
Volume:37
Page Range:49-66
Date:2006
Official Publication:https://doi.org/10.1016/S1569-2558(06)37003-8

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