Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Alternative splicing and genome complexity

Item Type:Article
Title:Alternative splicing and genome complexity
Creators Name:Brett, D., Pospisil, H., Valcarel, J., Reich, J. and Bork, P.
Abstract:Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.
Keywords:Alternative Splicing, Expressed Sequence Tags, Genetic Variation, Genome, Messenger RNA, Animals, Cattle, Mice, Rats
Source:Nature Genetics
ISSN:1061-4036
Publisher:Nature Publishing Group
Volume:30
Number:1
Page Range:29-30
Date:1 January 2002
Official Publication:https://doi.org/10.1038/ng803
PubMed:View item in PubMed

Repository Staff Only: item control page

Open Access
MDC Library