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| Item Type: | Article |
|---|---|
| Title: | proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes |
| Creators Name: | Fullam, A., Letunic, I., Schmidt, T.S.B., Ducarmon, Q.R., Karcher, N., Khedkar, S., Kuhn, M., Larralde, M., Maistrenko, O.M., Malfertheiner, L., Milanese, A., Rodrigues, J.F.M., Sanchis-López, C., Schudoma, C., Szklarczyk, D., Sunagawa, S., Zeller, G., Huerta-Cepas, J., von Mering, C., Bork, P. and Mende, D.R. |
| Abstract: | The interpretation of genomic, transcriptomic and other microbial 'omics data is highly dependent on the availability of well-annotated genomes. As the number of publicly available microbial genomes continues to increase exponentially, the need for quality control and consistent annotation is becoming critical. We present proGenomes3, a database of 907 388 high-quality genomes containing 4 billion genes that passed stringent criteria and have been consistently annotated using multiple functional and taxonomic databases including mobile genetic elements and biosynthetic gene clusters. proGenomes3 encompasses 41 171 species-level clusters, defined based on universal single copy marker genes, for which pan-genomes and contextual habitat annotations are provided. The database is available at http://progenomes.embl.de/. |
| Keywords: | Factual Databases, Genetic Databases, Genome, Genomics, Molecular Sequence Annotation, Prokaryotic Cells |
| Source: | Nucleic Acids Research |
| ISSN: | 0305-1048 |
| Publisher: | Oxford University Press |
| Volume: | 51 |
| Number: | D1 |
| Page Range: | D760-D766 |
| Date: | 6 January 2023 |
| Official Publication: | https://doi.org/10.1093/nar/gkac1078 |
| PubMed: | View item in PubMed |
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