Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome

Item Type:	Article
Title:	Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome
Creators Name:	Borowski, S. and Freitag, N. and Urban, I. and Michel, G. and Barrientos, G. and Blois, S.M.
Abstract:	Galectin-1 (gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, is differentially expressed at the feto-maternal interface and appears to be functionally polyvalent, with a wide range of biological activities. However, the contributions of maternal and/or feto-placental gal-1 to the signaling networks promoting a healthy pregnancy are still being elucidated. This chapter discusses the methods commonly employed to study the maternal or feto-placental contribution of gal-1 during pregnancy in mice. The methods described here can be used to decipher the specific role of each source, e.g., maternal and/or feto-placental derived gal-1 in the orchestration of pregnancy-associated processes.
Keywords:	Galectin-1, Maternal and Placental Galectin-1 Models, Pregnancy Outcome, Lectin Staining, In Vitro Fertilization, Animals, Mice
Source:	Methods in Molecular Biology
Series Name:	Methods in Molecular Biology
Title of Book:	Galectins
ISSN:	1064-3745
ISBN:	978-1-0716-2054-0
Publisher:	Springer / Humana Press
Volume:	2442
Page Range:	603-619
Date:	2022
Official Publication:	https://doi.org/10.1007/978-1-0716-2055-7_32
PubMed:	View item in PubMed

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