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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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10.1080/14756366.2021.1935917
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Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect
Taylor & Francis
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021. doi: 10.1080/14756366.2021.1935917
Arlt Birte
Mastrobuoni Guido
Wuenschel Jasmin
Astrahantseff Kathy
Eggert Angelika
Kempa Stefan
Deubzer Hedwig E.
Cancer cell metabolism
de novo serine synthesis pathway
citrate synthase
pulsed stable isotope-resolved metabolomics
thermal shift assay
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10.1080/14756366.2021.1935917
2021-06-30
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www.tandfonline.com
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