Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

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Item Type:	Article
Title:	Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants
Creators Name:	Texidó, G., Jacobs, H., Meiering, M., Kühn, R., Roes, J., Müller, W., Gilfillan, S., Fujiwara, H., Kikutani, H., Yoshida, N., Amakawa, R., Benoist, C., Mathis, D., Kishimoto, T., Mak, T.W. and Rajewsky, K.
Abstract:	We show through sequence analysis of rearranged immunoglobulin variable (Ig-V) region genes from memory B cells of mouse mutants generated by gene targeting that terminal deoxynucleotidyl transferase, CD23, interleukin-4, IgD and CD30 are dispensable for somatic hypermutation.
Keywords:	Hypermutation, Terminal Deoxynucleotidyl Transferase, CD23, Interleukin-4, IgD, Animals, Mice
Source:	European Journal of Immunology
ISSN:	0014-2980
Publisher:	Wiley
Volume:	26
Number:	8
Page Range:	1966-1969
Date:	August 1996
Official Publication:	https://doi.org/10.1002/eji.1830260843
PubMed:	View item in PubMed

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