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| Item Type: | Article |
|---|---|
| Title: | Cardiac chamber quantification using magnetic resonance imaging at 7 Tesla-a pilot study |
| Creators Name: | von Knobelsdorff-Brenkenhoff, F., Frauenrath, T., Prothmann, M., Dieringer, M.A., Hezel, F., Renz, W., Kretschel, K., Niendorf, T. and Schulz-Menger, J. |
| Abstract: | OBJECTIVES: Interest in cardiovascular magnetic resonance (CMR) at 7 T is motivated by the expected increase in spatial and temporal resolution, but the method is technically challenging. We examined the feasibility of cardiac chamber quantification at 7 T. METHODS: A stack of short axes covering the left ventricle was obtained in nine healthy male volunteers. At 1.5 T, steady-state free precession (SSFP) and fast gradient echo (FGRE) cine imaging with 7 mm slice thickness (STH) were used. At 7 T, FGRE with 7 mm and 4 mm STH were applied. End-diastolic volume, end-systolic volume, ejection fraction and mass were calculated. RESULTS: All 7 T examinations provided excellent blood/myocardium contrast for all slice directions. No significant difference was found regarding ejection fraction and cardiac volumes between SSFP at 1.5 T and FGRE at 7 T, while volumes obtained from FGRE at 1.5 T were underestimated. Cardiac mass derived from FGRE at 1.5 and 7 T was larger than obtained from SSFP at 1.5 T. Agreement of volumes and mass between SSFP at 1.5 T and FGRE improved for FGRE at 7 T when combined with an STH reduction to 4 mm. CONCLUSIONS: This pilot study demonstrates that cardiac chamber quantification at 7 T using FGRE is feasible and agrees closely with SSFP at 1.5 T. |
| Keywords: | Magnetic Resonance Imaging, Left Ventricle, Ultrahigh Field, Cardiac-Gated Imaging Techniques, Cine MRI |
| Source: | European Radiology |
| ISSN: | 0938-7994 |
| Publisher: | Springer |
| Volume: | 20 |
| Number: | 12 |
| Page Range: | 2844-2852 |
| Date: | December 2010 |
| Official Publication: | https://doi.org/10.1007/s00330-010-1888-2 |
| PubMed: | View item in PubMed |
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